CRISP1

Across TCGA patient cohorts, CRISP1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,847 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CRISP1-associated genes across cancer lineages are WDR20, RNU7-11P, and RIMS3. Each is linked with CRISP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CRISP1-to-partner and partner-to-CRISP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CRISP1 versus WDR20 in LUAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRISP1→partner) and Y-score (partner→CRISP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	WDR20 →	+0.374	+0.704	.001	.002	3	2
UCEC	RNU7-11P →	+2.455	+0.594	<.001	.001	3	2
LUAD	RIMS3 →	+0.953	+0.646	.008	.006	3	2
LUAD	SOX2 →	-1.793	-0.528	<.001	.003	3	2
CCRCC	P2RY8 →	-1.035	-0.356	<.001	.002	3	2
GBM	TMEM18 →	-0.469	-0.965	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,847 associations by consensus.

CRISP1 vs WDR20 — LUAD

Explore this scatter interactively →