Q-omics provides the consensus-scored CPSF1P1 profile across patient tissues and cancer cell-line models. CPSF1P1 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, CPSF1P1 is differentially expressed in 16, with the highest sampling consensus in COAD. Additionally, CPSF1P1 RNA expression shows 14,421 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight THCA, COAD, and TGCT as cancer lineages where CPSF1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CPSF1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CPSF1P1 survival associations across molecular data types. CPSF1P1 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CPSF1P1 RNA expression–survival associations across cancer types. High CPSF1P1 expression shows unfavorable associations in THCA, CESC, HNSC and UVM, but favorable associations in READ and LUSC. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify THCA as the clearest survival context for CPSF1P1 RNA expression.
This table summarizes CPSF1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for CPSF1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CPSF1P1 shows lower tumor expression in KICH and higher tumor expression in COAD, STAD, HNSC, UCEC and BLCA. The COAD box plot shows higher CPSF1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.657, t-test p < 0.001).
This table shows molecular features associated with CPSF1P1 in patient tissues and cancer cell lines. In patient samples, CPSF1P1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
