Across TCGA pan-cancer cohorts, CPSF1P1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of CPSF1P1’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CPSF1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CPSF1P1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
COAD, STAD, and HNSC are the cancer types where CPSF1P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CPSF1P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.