CORO2A

Across TCGA patient cohorts, CORO2A mutation is significantly associated with the RNA expression of many other genes, with 2,382 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CORO2A-associated genes across cancer lineages are RNVU1-28, TUBB4BP6, and RNA5SP93. Each is linked with CORO2A in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO2A-to-partner and partner-to-CORO2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-28 grouped by CORO2A-low versus CORO2A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO2A→partner) and Y-score (partner→CORO2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNVU1-28 →	+0.588	+1.519	<.001	.008	3	2
LGG	TUBB4BP6 →	+0.059	+7.977	<.001	.007	3	2
SKCM	RNA5SP93 →	+0.060	+4.228	<.001	.004	3	2
SKCM	RNU4-84P →	+0.060	+3.475	<.001	.002	3	2
LUSC	RNU6-895P →	+0.437	+7.593	<.001	<.001	3	2
UCEC	SNORD51 →	+0.621	+2.000	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,382 associations by consensus.

RNVU1-28 by CORO2A expression — UCEC

Explore this box plot interactively →