CORIN

Across TCGA patient cohorts, CORIN RNA expression is significantly associated with the protein abundance of many other proteins, with 15,062 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CORIN-associated proteins across cancer lineages are CTHRC1, VCAN, and SULF1. Each is linked with CORIN in more than 8 cancer types. Because this analysis shows association rather than direction, both CORIN-to-partner and partner-to-CORIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CORIN versus CTHRC1 in OV, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CORIN→partner) and Y-score (partner→CORIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CTHRC1 →	+1.083	+0.786	<.001	<.001	3	9
OV	VCAN →	+1.093	+0.607	<.001	<.001	3	8
OV	SULF1 →	+0.930	+0.664	<.001	<.001	3	8
OV	THBS2 →	+1.519	+0.683	<.001	<.001	3	8
BRCA	TIMP2 →	+0.853	+1.111	<.001	<.001	3	8
LSCC	TLN1_S2162 →	+0.806	+0.700	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,062 associations by consensus.

CORIN vs CTHRC1 — OV

Explore this scatter interactively →