CORIN

Across TCGA patient cohorts, CORIN protein abundance is significantly associated with the RNA expression of many other genes, with 285 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CORIN-associated genes across cancer lineages are BIRC7, ISM1, and LAMA1. Each is linked with CORIN in more than 1 cancer types. Because this analysis shows association rather than direction, both CORIN-to-partner and partner-to-CORIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CORIN versus BIRC7 in LUAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORIN→partner) and Y-score (partner→CORIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BIRC7 →	+1.141	+0.639	.004	.003	3	1
LUAD	ISM1 →	+1.486	+1.021	<.001	<.001	3	1
LUAD	LAMA1 →	+0.612	+0.758	.005	.001	3	1
LUAD	SCML2 →	-0.870	-0.688	.004	.001	3	1
LUAD	TGM5 →	+0.124	+0.736	.007	<.001	3	1
LUAD	PLIN3 →	+0.706	+0.817	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 285 associations by consensus.

CORIN vs BIRC7 — LUAD

Explore this scatter interactively →