COPS7B

Across TCGA patient cohorts, COPS7B mutation is significantly associated with the RNA expression of many other genes, with 1,193 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COPS7B-associated genes across cancer lineages are FABP7P2, RNA5SP485, and RNU6-820P. Each is linked with COPS7B in more than 2 cancer types. Because this analysis shows association rather than direction, both COPS7B-to-partner and partner-to-COPS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FABP7P2 grouped by COPS7B-low versus COPS7B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7B→partner) and Y-score (partner→COPS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FABP7P2 →	+0.174	+3.893	.008	.004	3	3
CESC	RNA5SP485 →	+0.285	+5.969	<.001	.002	3	2
LUSC	RNU6-820P →	+0.927	+5.474	<.001	.005	3	2
LUSC	RNU6-23P →	+0.585	+5.706	<.001	.003	3	2
UCEC	RNY1P1 →	+0.194	+3.113	<.001	.006	3	2
UCEC	MIR33B →	+0.302	+2.023	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,193 associations by consensus.

FABP7P2 by COPS7B expression — SKCM

Explore this box plot interactively →