COCH

Across TCGA patient cohorts, COCH RNA expression is significantly associated with the protein abundance of many other proteins, with 14,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COCH-associated proteins across cancer lineages are SPC24, CHAF1B, and TOP2A. Each is linked with COCH in more than 6 cancer types. Because this analysis shows association rather than direction, both COCH-to-partner and partner-to-COCH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COCH versus SPC24 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COCH→partner) and Y-score (partner→COCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPC24 →	+0.677	+0.746	<.001	.001	3	6
GBM	CHAF1B →	+0.500	+0.738	.003	<.001	2	7
LSCC	TOP2A →	+0.828	+0.992	<.001	<.001	3	6
GBM	TPX2 →	+0.707	+0.832	<.001	.002	3	6
HNSC	RIF1 →	+0.387	+1.022	<.001	.001	3	5
LSCC	SMC2 →	+0.506	+1.088	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,933 associations by consensus.

COCH vs SPC24 — GBM

Explore this scatter interactively →