COCH

Across TCGA patient cohorts, COCH protein abundance is significantly associated with the RNA expression of many other genes, with 11,410 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COCH-associated genes across cancer lineages are CXXC5, FAM201A, and ZNF746. Each is linked with COCH in more than 3 cancer types. Because this analysis shows association rather than direction, both COCH-to-partner and partner-to-COCH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COCH versus CXXC5 in OV, with a Pearson correlation of -0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COCH→partner) and Y-score (partner→COCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CXXC5 →	-1.711	-1.302	.008	.009	3	4
HNSC	FAM201A →	+1.482	+1.622	<.001	.007	3	4
HNSC	ZNF746 →	+1.234	+1.690	<.001	.003	3	3
HNSC	MIR554 →	+1.873	+1.519	<.001	.002	3	3
HNSC	RPS4XP14 →	+1.138	+2.071	<.001	<.001	3	3
HNSC	MPP6 →	+1.110	+1.557	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,410 associations by consensus.

COCH vs CXXC5 — OV

Explore this scatter interactively →