Q-omics provides the consensus-scored MIR554 profile across patient tissues and cancer cell-line models. MIR554 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, MIR554 is differentially expressed in 12, with the highest sampling consensus in HNSC. Additionally, MIR554 RNA expression shows 13,886 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight COAD, HNSC, and LSCC as cancer lineages where MIR554 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR554 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR554 survival associations across molecular data types. MIR554 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR554 RNA expression–survival associations across cancer types. High MIR554 expression shows unfavorable associations in COAD, KIRC, LIHC, STAD and KICH, but favorable associations in BRCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify COAD as the clearest survival context for MIR554 RNA expression.
This table summarizes MIR554 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR554. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR554 shows lower tumor expression in KICH and KIRC and higher tumor expression in HNSC, BLCA, BRCA and LUSC. The HNSC box plot shows higher MIR554 RNA expression in tumor versus normal tissue (log2 FC = +0.593, t-test p < 0.001).
This table shows molecular features associated with MIR554 in patient tissues and cancer cell lines. In patient samples, MIR554 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
