CNOT9

Across TCGA patient cohorts, CNOT9 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,013 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CNOT9-associated proteins across cancer lineages are FEN1, ILKAP, and MCM3. Each is linked with CNOT9 in more than 8 cancer types. Because this analysis shows association rather than direction, both CNOT9-to-partner and partner-to-CNOT9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNOT9 versus FEN1 in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNOT9→partner) and Y-score (partner→CNOT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FEN1 →	+0.604	+0.381	<.001	<.001	3	9
GBM	ILKAP →	+0.372	+0.322	<.001	<.001	3	9
OV	MCM3 →	+0.826	+0.520	<.001	<.001	3	9
GBM	MCM7 →	+0.614	+0.254	<.001	<.001	3	9
COAD	CHAF1B →	+0.791	+0.605	<.001	.001	3	8
OV	DNMT1 →	+0.405	+0.374	.002	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,013 associations by consensus.

CNOT9 vs FEN1 — GBM

Explore this scatter interactively →