Across TCGA patient cohorts, CMSS1 mutation is significantly associated with the RNA expression of many other genes, with 463 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMSS1-associated genes across cancer lineages are RNU6ATAC30P, HMGN2P32, and RN7SL248P. Each is linked with CMSS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CMSS1-to-partner and partner-to-CMSS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMSS1→partner) and Y-score (partner→CMSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6ATAC30P →	+0.383	+5.625	<.001	.004	3	3
COAD	HMGN2P32 →	+1.048	+3.589	<.001	.009	3	3
UCEC	RN7SL248P →	+0.103	+4.022	<.001	<.001	3	2
STAD	RNU6-162P →	+0.701	+5.274	<.001	.006	3	2
UCEC	SNORD82 →	+0.480	+1.940	.001	.008	3	2
UCEC	BNIP3P6 →	+0.033	+4.571	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 463 associations by consensus.

Exploration

CMSS1 survival (RNA) · tumor vs normal (RNA) · all CMSS1 data types