CLRN1-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLRN1-AS1 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLRN1-AS1-associated genes across cancer lineages are MIR208B, MIR5708, and SNRPCP20. Each is linked with CLRN1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLRN1-AS1-to-partner and partner-to-CLRN1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR208B grouped by CLRN1-AS1-low versus CLRN1-AS1-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLRN1-AS1→partner) and Y-score (partner→CLRN1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAMIR208B →+0.548+5.247<.001.00631
UCECMIR5708 →+0.622+5.877<.001.00131
UCECSNRPCP20 →+0.534+4.633<.001.00431
UCECPRAMEF28P →+0.138+4.551<.001.00931
UCECRN7SL248P →+0.220+5.722<.001.00131
UCECOR2D2 →+0.165+4.633.005.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

MIR208B by CLRN1-AS1 expression — ESCA

Box plot of MIR208B in CLRN1-AS1-low vs CLRN1-AS1-high samples in ESCA.

Explore this box plot interactively →

Exploration