CLRN1-AS1

Across TCGA pan-cancer cohorts, CLRN1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CLRN1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CLRN1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CLRN1-AS1 is over-expressed in tumor, although a few such as LIHC and UCEC show the opposite, repressed pattern.

BRCA, KIRC, and LIHC are the cancer types where CLRN1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLRN1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	+0.224	<.001	6	view →
KIRC	All	All	+0.062	<.001	6	view →
LIHC	Female	II,III,IV	−0.506	<.001	4	view →
UCEC	All	All	−0.240	.049	2	view →
CHOL	Female	All	−0.366	.034	1	view →
HNSC	Male	All	+0.017	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CLRN1-AS1–BRCA

Open the BRCA breakdown →