CLRN1-AS1

Across TCGA pan-cancer cohorts, CLRN1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CLRN1-AS1 data layer compared with 2 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher CLRN1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CLRN1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and CESC show a favorable association.

BRCA, THCA, and CESC are the cancer types where CLRN1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	III,IV	0.926	0.746	<.001	103	view →
THCA	OS	Median	II,III,IV	0.900	0.990	.001	54	view →
CESC	OS	Tertile	IV	0.682	0.110	.009	24	view →
BLCA	OS	Tertile	IV	0.214	0.544	.006	18	view →
KICH	DFS	Tertile	II,III,IV	0.697	0.951	.026	16	view →
UCEC	DFS	Tertile	All	0.861	0.920	.006	14	view →
THYM	DFS	Tertile	All	0.932	0.647	.010	13	view →
ESCA	OS	Quartile	IV	0.195	0.709	.017	12	view →
UCS	OS	Tertile	II,III,IV	0.759	0.373	.017	12	view →
SARC	DFS	Median	All	0.698	0.547	.007	12	view →
ACC	OS	Median	II,III,IV	0.378	0.866	.010	8	view →
PRAD	DFS	Median	All	0.646	0.851	.014	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CLRN1-AS1–BRCA (OS)

Open the BRCA breakdown →