CLDND2

Across TCGA patient cohorts, CLDND2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CLDND2-associated genes across cancer lineages are GLUD1P9, OFD1P11Y, and MCCD1. Each is linked with CLDND2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDND2-to-partner and partner-to-CLDND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLUD1P9 grouped by CLDND2-low versus CLDND2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDND2→partner) and Y-score (partner→CLDND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GLUD1P9 →	+0.034	+7.816	<.001	.008	3	1
SKCM	OFD1P11Y →	+0.034	+7.816	<.001	.008	3	1
COAD	MCCD1 →	+0.132	+5.126	<.001	.001	3	1
COAD	TRDJ2 →	+1.427	+4.384	<.001	.006	3	1
COAD	RNA5SP63 →	+0.927	+4.870	<.001	.002	3	1
COAD	LNCNEF →	+0.155	+4.870	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GLUD1P9 by CLDND2 expression — SKCM

Explore this box plot interactively →