CLDND2

Across TCGA pan-cancer cohorts, CLDND2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CLDND2 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CLDND2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CLDND2 expression acts as an unfavorable survival marker, although some lineages such as CESC and ESCA show a favorable association.

CESC, KIRC, and COAD are the cancer types where CLDND2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.719	0.393	<.001	100	view →
KIRC	DFS	Tertile	All	0.541	0.722	<.001	96	view →
COAD	OS	Median	III,IV	0.708	0.848	.004	52	view →
LGG	DFS	Median	All	0.642	0.806	<.001	43	view →
KIRP	DFS	Quartile	II,III,IV	0.252	1.000	.007	32	view →
ACC	DFS	Quartile	II,III,IV	0.443	0.853	.016	24	view →
LIHC	OS	Quartile	All	0.381	0.687	<.001	21	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	18	view →
PAAD	OS	Tertile	All	0.545	0.250	.005	14	view →
UVM	DFS	Median	All	0.294	0.666	.012	11	view →
SKCM	OS	Tertile	III,IV	0.587	0.257	.005	11	view →
THCA	DFS	Median	All	0.968	0.916	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CLDND2–CESC (DFS)

Open the CESC breakdown →