CKAP5

Across TCGA cell cohorts, CKAP5 mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CKAP5-associated genes across cancer lineages are C10orf71, MROH5, and TAS2R41. Each is linked with CKAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CKAP5-to-partner and partner-to-CKAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf71 grouped by CKAP5-low versus CKAP5-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP5→partner) and Y-score (partner→CKAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C10orf71 →	+0.006	+4.906	<.001	.006	3	2
PANCREAS	MROH5 →	+0.023	+5.000	<.001	.006	3	2
STOMACH	TAS2R41 →	+0.068	+4.432	<.001	.003	3	2
BLOOD_Leukemia	FAM98C →	+0.654	+3.489	.001	.001	3	2
BLOOD_Leukemia	RPL3L →	+0.079	+3.385	.002	.004	3	2
BLOOD_Lymphoma	OR2L8 →	+0.024	+4.169	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

C10orf71 by CKAP5 expression — OESOPHAGUS

Explore this box plot interactively →