CHRNB3

Across TCGA cell cohorts, CHRNB3 RNA expression is significantly associated with the RNA expression of many other genes, with 848 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible CHRNB3-associated genes across cancer lineages are SPATA31A1, OR5K1, and TRIM42. Each is linked with CHRNB3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHRNB3-to-partner and partner-to-CHRNB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNB3 versus SPATA31A1 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.96.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNB3→partner) and Y-score (partner→CHRNB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	SPATA31A1 →	+0.170	+0.024	.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR5K1 →	+0.048	+0.056	.001	<.001	3	3
STOMACH	TRIM42 →	+0.049	+0.009	<.001	<.001	3	3
BLOOD_Leukemia	C10orf71 →	+0.368	+0.006	<.001	.001	3	3
LUNG_NSCLC_LUSC	SCN10A →	+0.019	+0.019	.003	<.001	3	3
LUNG_NSCLC_LUSC	SPATA31A6 →	+0.139	+0.016	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 848 associations by consensus.

CHRNB3 vs SPATA31A1 — LUNG_NSCLC_LUSC

Explore this scatter interactively →