CHDH

Across TCGA patient cohorts, CHDH protein abundance is significantly associated with the RNA expression of many other genes, with 14,843 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHDH-associated genes across cancer lineages are IL17RB, CLEC2B, and FMO5. Each is linked with CHDH in more than 8 cancer types. Because this analysis shows association rather than direction, both CHDH-to-partner and partner-to-CHDH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHDH versus IL17RB in BRCA, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHDH→partner) and Y-score (partner→CHDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL17RB →	+1.408	+1.007	<.001	<.001	3	9
OV	CLEC2B →	-1.220	-0.685	<.001	<.001	3	6
PDAC	FMO5 →	+1.092	+0.486	<.001	<.001	3	6
UCEC	CACNA1D →	+1.058	+0.570	<.001	<.001	3	6
BRCA	CIP2A →	-0.673	-0.519	<.001	<.001	3	6
UCEC	CAVIN4 →	-0.534	-0.391	.005	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,843 associations by consensus.

CHDH vs IL17RB — BRCA

Explore this scatter interactively →