CHDH

Across TCGA patient cohorts, CHDH mutation is significantly associated with the RNA expression of many other genes, with 403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHDH-associated genes across cancer lineages are LINC02855, MIR3908, and RN7SL471P. Each is linked with CHDH in more than 1 cancer types. Because this analysis shows association rather than direction, both CHDH-to-partner and partner-to-CHDH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02855 grouped by CHDH-low versus CHDH-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHDH→partner) and Y-score (partner→CHDH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02855 →	+0.057	+2.705	.003	.008	3	2
SKCM	MIR3908 →	+0.221	+4.385	<.001	<.001	3	2
UCEC	RN7SL471P →	+0.205	+2.503	<.001	.004	3	2
COAD	PTP4A1P3 →	+0.293	+4.962	.001	.003	3	2
COAD	MIR4759 →	+0.519	+5.332	<.001	.002	3	2
SKCM	RNU6-642P →	+0.296	+2.906	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 403 associations by consensus.

LINC02855 by CHDH expression — SKCM

Explore this box plot interactively →