CEP97

Across TCGA cell cohorts, CEP97 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible CEP97-associated genes across cancer lineages are OR2D3, GNAT3, and SPRR5. Each is linked with CEP97 in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP97-to-partner and partner-to-CEP97 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by CEP97-low versus CEP97-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP97→partner) and Y-score (partner→CEP97) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2D3 →	+0.028	+3.990	<.001	.003	3	2
BLOOD_Myeloma	GNAT3 →	+0.030	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SPRR5 →	+0.320	+4.807	<.001	.006	3	1
OVARY	OR2J3 →	+0.017	+3.938	.004	.005	3	1
STOMACH	IQCJ →	+0.083	+5.285	<.001	.003	3	1
LUNG_NSCLC_LUAD	APOC4 →	+0.066	+6.266	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR2D3 by CEP97 expression — OVARY

Explore this box plot interactively →