Q-omics provides the consensus-scored OR2J3 profile across patient tissues and cancer cell-line models. OR2J3 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, OR2J3 is differentially expressed in 2, with the highest sampling consensus in PRAD. Additionally, OR2J3 RNA expression shows 8,347 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, PRAD, and THYM as cancer lineages where OR2J3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR2J3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR2J3 survival associations across molecular data types. OR2J3 RNA expression shows survival associations in the most cancer types (15), followed by mutation status (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR2J3 RNA expression–survival associations across cancer types. High OR2J3 expression shows unfavorable associations in KIRC, HNSC, STAD, THCA, READ and COAD. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for OR2J3 RNA expression.
This table summarizes OR2J3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in PRAD for RNA.
This table ranks reproducible tumor–normal expression differences for OR2J3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR2J3 shows higher tumor expression in PRAD and THCA. The PRAD box plot shows higher OR2J3 RNA expression in tumor versus normal tissue (log2 FC = +0.033, t-test p = .022).
This table shows molecular features associated with OR2J3 in patient tissues and cancer cell lines. In patient samples, OR2J3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, OR2J3 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and LARGE_INTESTINE.
