Across TCGA pan-cancer cohorts, OR2J3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR2J3’s most consistent transcriptional readouts.
The strongest signal is observed in prostate adenocarcinoma (PRAD), where OR2J3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OR2J3 is over-expressed in tumor.
PRAD and THCA are the cancer types where OR2J3 tumor–normal differential expression is most reproducible.