OR2J3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR2J3 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2J3-associated genes across cancer lineages are Caveolin-1, eIF4E, and HSP70. Each is linked with OR2J3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2J3-to-partner and partner-to-OR2J3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2J3→partner) and Y-score (partner→OR2J3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCaveolin-1 →-0.587-3.169.044.01832
UCECeIF4E →+0.185+1.906.028.01622
UCECHSP70 →-0.324-2.990.045.03631
UCECJNK_pT183_Y185 →-0.189-2.401.005.00331
UCECJNK2 →+0.254+1.906.001.01631
UCECMEK1 →+0.500+3.459<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration