CEP97

Across TCGA pan-cancer cohorts, CEP97 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CEP97 data layer compared with 6 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher CEP97 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CEP97 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

KICH, ACC, and LIHC are the cancer types where CEP97 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.719	1.000	<.001	92	view →
ACC	DFS	Median	All	0.374	0.778	<.001	83	view →
LIHC	DFS	Median	All	0.452	0.633	<.001	62	view →
KIRC	DFS	Quartile	All	0.913	0.682	<.001	42	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
MESO	DFS	Median	IV	0.172	0.485	.002	18	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	18	view →
SCLC	OS	Median	II,III,IV	0.713	0.410	.004	15	view →
LUSC	DFS	Quartile	All	0.814	0.699	.010	14	view →
SKCM	OS	Quartile	All	0.405	0.224	.002	12	view →
THYM	OS	Tertile	All	1.000	0.721	.006	12	view →
GBM	DFS	Quartile	All	0.460	0.155	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CEP97–KICH (OS)

Open the KICH breakdown →