Q-omics provides the consensus-scored SPRR5 profile across patient tissues and cancer cell-line models. Additionally, SPRR5 protein abundance shows 6,299 significant gene co-expression associations, with the highest sampling consensus in HNSC.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for SPRR5 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Cross-omics associations

This table shows molecular features associated with SPRR5 in patient tissues and cancer cell lines. In patient samples, SPRR5 shows the broadest associations at the RNA and protein expression levels, with HNSC recurring as the lineage with the largest associated feature set. In cancer cell lines, SPRR5 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼Protein (mass-spec)
RNA	6,299	HNSC (5618)	view →
Protein (mass-spec)	5,541	HNSC (4748)	view →
▼RNA
Protein (mass-spec)	5,309	HNSC (3782)	view →
Function (mass-spec)	408	HNSC (186)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	917	UPPER_AERODIGESTIVE_TRACT (378)	view →
Function (RNA)	181	UPPER_AERODIGESTIVE_TRACT (150)	view →