CEP85L

Across TCGA cell cohorts, CEP85L mutation is significantly associated with the RNA expression of many other genes, with 163 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CEP85L-associated genes across cancer lineages are OR1L3, FAM47C, and BLVRA. Each is linked with CEP85L in more than 1 cancer types. Because this analysis shows association rather than direction, both CEP85L-to-partner and partner-to-CEP85L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L3 grouped by CEP85L-low versus CEP85L-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CEP85L→partner) and Y-score (partner→CEP85L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1
SKIN	FAM47C →	+0.006	+4.977	<.001	.007	3	1
LARGE_INTESTINE	BLVRA →	+1.212	+3.299	.009	.004	3	1
LARGE_INTESTINE	LMNB1 →	+0.697	+3.299	.003	.004	3	1
LARGE_INTESTINE	ALDH6A1 →	+1.020	+3.064	.001	.009	3	1
LARGE_INTESTINE	GRSF1 →	+0.504	+3.212	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 163 associations by consensus.

OR1L3 by CEP85L expression — SKIN

Explore this box plot interactively →