CEP85L

Across TCGA pan-cancer cohorts, CEP85L RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CEP85L data layer compared with 5 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CEP85L RNA is associated with better overall survival. In most high-consensus cancer types, elevated CEP85L expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCS show a favorable association.

SKCM, UCS, and LUSC are the cancer types where CEP85L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.834	0.698	<.001	82	view →
UCS	DFS	Tertile	II,III,IV	0.494	0.148	.007	36	view →
LUSC	DFS	Tertile	II,III,IV	0.563	0.924	.001	34	view →
LUAD	DFS	Tertile	IV	0.555	0.973	.014	33	view →
ACC	DFS	Quartile	III,IV	0.697	0.072	.001	21	view →
SCLC	OS	Median	II,III,IV	0.304	0.629	.008	21	view →
CHOL	DFS	Median	All	0.636	0.232	.010	21	view →
THYM	OS	Median	All	1.000	0.689	<.001	17	view →
CESC	DFS	Median	All	0.676	0.799	.015	14	view →
KIRC	DFS	Median	IV	0.215	0.489	.003	13	view →
KICH	DFS	Tertile	II,III,IV	0.541	0.895	.016	11	view →
STAD	DFS	Quartile	IV	0.093	0.473	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CEP85L–SKCM (OS)

Open the SKCM breakdown →