CENPB

Across TCGA patient cohorts, CENPB mutation is significantly associated with the RNA expression of many other genes, with 1,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CENPB-associated genes across cancer lineages are MIR6815, RNA5SP325, and RNU6-391P. Each is linked with CENPB in more than 2 cancer types. Because this analysis shows association rather than direction, both CENPB-to-partner and partner-to-CENPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6815 grouped by CENPB-low versus CENPB-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CENPB→partner) and Y-score (partner→CENPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR6815 →	+0.475	+6.197	<.001	.001	3	3
CESC	RNA5SP325 →	+0.344	+6.837	<.001	<.001	3	2
UCEC	RNU6-391P →	+0.197	+3.027	<.001	.007	3	2
UCEC	IGHD4-4 →	+0.534	+3.226	<.001	.005	3	2
SKCM	NDUFB10P1 →	+0.154	+4.177	<.001	.004	3	2
UCEC	RNA5SP419 →	+0.723	+2.492	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,747 associations by consensus.

MIR6815 by CENPB expression — LUAD

Explore this box plot interactively →