CDCA4

Across TCGA patient cohorts, CDCA4 mutation is significantly associated with the RNA expression of many other genes, with 219 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CDCA4-associated genes across cancer lineages are RNU6-1133P, PPIAP48, and MIR4474. Each is linked with CDCA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CDCA4-to-partner and partner-to-CDCA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1133P grouped by CDCA4-low versus CDCA4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CDCA4→partner) and Y-score (partner→CDCA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-1133P →	+0.431	+5.669	<.001	.003	3	2
COAD	PPIAP48 →	+0.217	+3.830	<.001	.002	3	2
COAD	MIR4474 →	+0.566	+3.636	.003	.006	3	2
UCEC	SNORD8 →	+0.787	+2.511	<.001	.001	3	2
UCEC	H2BC14 →	+0.701	+2.595	<.001	.006	3	2
HNSC	IGHD6-19 →	+1.463	+4.452	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 219 associations by consensus.

RNU6-1133P by CDCA4 expression — CESC

Explore this box plot interactively →