CDCA4

Across TCGA pan-cancer cohorts, CDCA4 RNA is linked to patient survival in 29 of 34 cancer types, making it the most broadly survival-associated CDCA4 data layer compared with 4 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher CDCA4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CDCA4 expression acts as an unfavorable survival marker, although some lineages such as THYM and ESCA show a favorable association.

MESO, ACC, and KIRP are the cancer types where CDCA4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.395	0.673	<.001	111	view →
ACC	DFS	Median	All	0.521	0.792	<.001	109	view →
KIRP	DFS	Tertile	All	0.764	0.933	<.001	90	view →
LIHC	OS	Tertile	All	0.583	0.777	<.001	81	view →
PAAD	DFS	Tertile	All	0.382	0.622	<.001	65	view →
BLCA	OS	Quartile	All	0.629	0.811	.006	51	view →
LGG	OS	Median	All	0.747	0.877	<.001	49	view →
UVM	DFS	Tertile	III,IV	0.084	1.000	.004	46	view →
SARC	DFS	Median	All	0.424	0.603	<.001	40	view →
LUAD	OS	Quartile	All	0.344	0.779	.001	35	view →
LAML	DFS	Quartile	All	0.445	0.744	.003	30	view →
HNSC	OS	Tertile	III,IV	0.550	0.721	.003	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 29 lineages.

CDCA4–MESO (OS)

Open the MESO breakdown →