peptidylprolyl isomerase A pseudogene 48Genealiases: []
Q-omics provides the consensus-scored PPIAP48 profile across patient tissues and cancer cell-line models. PPIAP48 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, PPIAP48 is differentially expressed in 2, with the highest sampling consensus in LIHC. Additionally, PPIAP48 RNA expression shows 6,655 significant pathway-activity associations, with the highest sampling consensus in LGG. Together, these results highlight MESO, LIHC, and LGG as cancer lineages where PPIAP48 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PPIAP48 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PPIAP48 survival associations across molecular data types. PPIAP48 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PPIAP48 RNA expression–survival associations across cancer types. High PPIAP48 expression shows unfavorable associations in MESO, LIHC, LGG, STAD, UCEC and THYM. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify MESO as the clearest survival context for PPIAP48 RNA expression.
This table summarizes PPIAP48 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for PPIAP48. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PPIAP48 shows higher tumor expression in LIHC and KIRC. The LIHC box plot shows higher PPIAP48 RNA expression in tumor versus normal tissue (log2 FC = +0.013, t-test p = .025).
This table shows molecular features associated with PPIAP48 in patient tissues and cancer cell lines. In patient samples, PPIAP48 shows the broadest associations at the RNA and protein expression levels, with LGG recurring as the lineage with the largest associated feature set.
