PPIAP48

Across TCGA patient cohorts, PPIAP48 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,655 significant associations in total. LGG shows the largest number of these associations.

The most reproducible PPIAP48-associated GO terms across cancer lineages are Positive regulation of protein catabolic process, Regulation of myeloid cell differentiation, and Viral gene expression. Each is linked with PPIAP48 in more than 13 cancer types. Because this analysis shows association rather than direction, both PPIAP48-to-partner and partner-to-PPIAP48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein catabolic process grouped by PPIAP48-low versus PPIAP48-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPIAP48→partner) and Y-score (partner→PPIAP48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of protein catabolic process →	+0.042	+0.051	.001	.004	2	14
ESCA	Regulation of myeloid cell differentiation →	+0.036	+0.057	.001	.001	2	13
THYM	Viral gene expression →	+0.045	+0.044	<.001	<.001	3	12
THYM	Regulation of binding →	+0.037	+0.046	<.001	<.001	3	11
ESCA	Bone development →	+0.034	+0.059	<.001	<.001	2	12
ESCA	Cellular response to radiation →	+0.051	+0.085	<.001	.002	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,655 associations by consensus.

Positive regulation of protein catabolic process by PPIAP48 expression — ESCA

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