CCNL1

Across TCGA patient cohorts, CCNL1 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,653 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNL1-associated proteins across cancer lineages are RFC4, RFC2, and EMG1. Each is linked with CCNL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCNL1-to-partner and partner-to-CCNL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNL1 versus RFC4 in LSCC, with a Pearson correlation of 0.66.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNL1→partner) and Y-score (partner→CCNL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC4 →	+0.539	+0.345	<.001	<.001	3	7
LSCC	RFC2 →	+0.469	+0.325	<.001	<.001	3	6
BRCA	EMG1 →	+0.533	+0.417	<.001	<.001	3	6
BRCA	GATAD2B →	+0.332	+0.255	<.001	<.001	3	6
UCEC	TPX2 →	+0.822	+0.285	<.001	<.001	3	6
GBM	KIFC1 →	+0.651	+0.264	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,653 associations by consensus.

CCNL1 vs RFC4 — LSCC

Explore this scatter interactively →