CCNL1

Across TCGA pan-cancer cohorts, CCNL1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CCNL1 data layer compared with 5 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CCNL1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCNL1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

ACC, KIRC, and BLCA are the cancer types where CCNL1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.401	0.756	<.001	85	view →
KIRC	DFS	Median	II,III,IV	0.410	0.619	<.001	76	view →
BLCA	DFS	Tertile	III,IV	0.383	0.221	.005	65	view →
LGG	DFS	Tertile	All	0.758	0.890	<.001	27	view →
UVM	DFS	Quartile	III,IV	0.234	0.832	.005	27	view →
SKCM	DFS	Tertile	All	0.229	0.145	.013	27	view →
STAD	DFS	Quartile	IV	0.132	0.638	.014	19	view →
LIHC	OS	Median	All	0.419	0.583	.002	19	view →
ESCA	OS	Median	IV	0.222	0.698	.006	17	view →
THCA	DFS	Tertile	III,IV	0.880	0.990	.009	14	view →
OV	DFS	Median	III,IV	0.484	0.575	.014	14	view →
UCEC	DFS	Tertile	All	0.800	0.873	.026	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CCNL1–ACC (DFS)

Open the ACC breakdown →