CCNL1

Across TCGA pan-cancer cohorts, CCNL1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCNL1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CCNL1 RNA is repressed in tumor relative to normal tissue. In most cancer types CCNL1 is over-expressed in tumor, although a few such as BRCA and LUAD show the opposite, repressed pattern.

BRCA, LUAD, and THCA are the cancer types where CCNL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCNL1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.879	<.001	6	view →
LUAD	All	All	−0.534	<.001	6	view →
THCA	Female	All	−0.598	<.001	5	view →
KICH	All	All	−0.694	<.001	4	view →
COAD	Male	II,III,IV	+0.557	<.001	4	view →
KIRC	All	All	+0.319	.001	4	view →
HNSC	Male	III,IV	+0.658	.032	3	view →
CHOL	All	All	+1.002	<.001	2	view →
ESCA	Female	All	+0.939	.001	2	view →
READ	Female	All	+0.765	.013	2	view →
UCEC	All	All	−0.486	.011	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CCNL1–BRCA

Open the BRCA breakdown →