CCL13

Across TCGA patient cohorts, CCL13 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL13-associated genes across cancer lineages are FAM25C, RNU6-643P, and RNU6-456P. Each is linked with CCL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL13-to-partner and partner-to-CCL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM25C grouped by CCL13-low versus CCL13-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL13→partner) and Y-score (partner→CCL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM25C →	+0.183	+5.020	.009	.009	3	1
SKCM	RNU6-643P →	+0.312	+7.816	<.001	.008	3	1
SKCM	RNU6-456P →	+0.313	+7.816	<.001	.008	3	1
SKCM	MIR544A →	+0.357	+7.816	<.001	.008	3	1
UCEC	URGCP-MRPS24 →	+0.363	+3.969	<.001	.001	3	1
SKCM	RN7SKP157 →	+0.134	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

FAM25C by CCL13 expression — BRCA

Explore this box plot interactively →