CCL13

Across TCGA pan-cancer cohorts, CCL13 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCL13 data layer compared with 2 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CCL13 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CCL13 expression acts as an unfavorable survival marker, although some lineages such as SKCM and UCEC show a favorable association.

SKCM, KIRC, and KIRP are the cancer types where CCL13 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.418	0.259	<.001	83	view →
KIRC	DFS	Quartile	II,III,IV	0.372	0.620	.001	39	view →
KIRP	DFS	Quartile	All	0.784	1.000	.017	32	view →
MESO	OS	Median	All	0.267	0.697	.007	30	view →
UCEC	OS	Quartile	All	0.805	0.352	<.001	30	view →
BLCA	OS	Median	IV	0.681	0.493	.003	25	view →
LUSC	DFS	Quartile	II,III,IV	0.467	0.897	.003	20	view →
LUAD	DFS	Median	All	0.703	0.623	.014	19	view →
GBM	DFS	Tertile	All	0.195	0.331	.007	15	view →
SARC	OS	Quartile	All	0.829	0.685	.018	9	view →
OV	OS	Quartile	II,III,IV	0.916	0.824	.031	8	view →
ACC	DFS	Tertile	All	0.709	0.348	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCL13–SKCM (OS)

Open the SKCM breakdown →