CCL13

Across TCGA pan-cancer cohorts, CCL13 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of CCL13’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCL13 RNA is repressed in tumor relative to normal tissue. In most cancer types CCL13 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, THCA, and LUSC are the cancer types where CCL13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCL13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	−2.019	<.001	10	view →
THCA	Male	III,IV	+2.531	<.001	9	view →
LUSC	All	II,III,IV	−1.589	<.001	7	view →
HNSC	All	II,III,IV	+1.036	.002	7	view →
KICH	Male	II,III,IV	−1.030	<.001	7	view →
BRCA	All	III,IV	−2.256	<.001	6	view →
LIHC	All	All	+0.449	<.001	5	view →
KIRP	Male	All	−0.585	.021	3	view →
BLCA	All	III,IV	−1.202	.023	2	view →
LUAD	All	All	+0.640	.033	2	view →
PRAD	All	All	−0.238	.022	2	view →
READ	Female	All	−1.853	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

CCL13–COAD

Open the COAD breakdown →