Q-omics provides the consensus-scored RNU6-456P profile across patient tissues and cancer cell-line models. RNU6-456P expression is associated with patient survival in 5 of 34 cancer types, with the highest sampling consensus in ACC. Additionally, RNU6-456P RNA expression shows 7,521 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight ACC, and COAD as cancer lineages where RNU6-456P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-456P survival associations across molecular data types. RNU6-456P RNA expression shows survival associations in the most cancer types (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-456P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	5	ACC (39)	view →

This table ranks reproducible RNU6-456P RNA expression–survival associations across cancer types. High RNU6-456P expression shows unfavorable associations in ACC, STAD, LGG, THCA and UCEC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for RNU6-456P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.164	0.835	<.001	39	view →
STAD	OS	Tertile	All	0.289	0.558	.032	18	view →
LGG	DFS	Tertile	All	0.110	0.826	<.001	18	view →
THCA	OS	Tertile	III,IV	0.367	0.901	.017	9	view →
UCEC	DFS	Tertile	All	0.653	0.842	.027	6	view →

Pink = unfavorable, green = favorable. all 5 lineages →

RNU6-456P-ACC (OS)

Kaplan–Meier survival curve for RNU6-456P RNA expression in ACC: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with RNU6-456P in patient tissues and cancer cell lines. In patient samples, RNU6-456P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,521	COAD (4578)	view →
Function (RNA)	5,455	STAD (5225)	view →