Across TCGA cell cohorts, CCER1 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCER1-associated genes across cancer lineages are DEFB103A, DEFB103B, and LHX8. Each is linked with CCER1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCER1-to-partner and partner-to-CCER1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCER1→partner) and Y-score (partner→CCER1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DEFB103A →	+0.010	+3.969	.002	.009	3	2
BLOOD_Leukemia	DEFB103B →	+0.010	+3.969	.002	.009	3	2
BLOOD_Leukemia	LHX8 →	+0.284	+3.807	<.001	.007	3	1
BLOOD_Leukemia	SPRR1A →	+0.179	+4.201	<.001	.001	3	1
BLOOD_Leukemia	PSG9 →	+0.034	+4.123	<.001	.003	3	1
BLOOD_Leukemia	SHISA6 →	+0.019	+3.684	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

CCER1 survival (RNA) · tumor vs normal (RNA) · all CCER1 data types