Across TCGA pan-cancer cohorts, CCER1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCER1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CCER1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCER1 is over-expressed in tumor.
HNSC and LUSC are the cancer types where CCER1 tumor–normal differential expression is most reproducible.