CCDC96

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC96 mutation is significantly associated with the RNA expression of many other genes, with 387 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC96-associated genes across cancer lineages are CA5A, PCDH11Y, and ANKRD54. Each is linked with CCDC96 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC96-to-partner and partner-to-CCDC96 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CA5A grouped by CCDC96-low versus CCDC96-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC96→partner) and Y-score (partner→CCDC96) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTCA5A →+0.020+5.087<.001.00431
URINARY_TRACTPCDH11Y →+0.016+5.087<.001.00431
LARGE_INTESTINEANKRD54 →+0.588+3.588<.001<.00131
LARGE_INTESTINECBY1 →+0.587+2.451.001.00931
LARGE_INTESTINEL3MBTL2 →+0.682+3.169<.001.00631
LARGE_INTESTINETRMU →+0.630+3.502.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 387 associations by consensus.

CA5A by CCDC96 expression — URINARY_TRACT

Box plot of CA5A in CCDC96-low vs CCDC96-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration