CCDC83

Across TCGA cell cohorts, CCDC83 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCDC83-associated genes across cancer lineages are PRAMEF9, CCL18, and H1-7. Each is linked with CCDC83 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC83-to-partner and partner-to-CCDC83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF9 grouped by CCDC83-low versus CCDC83-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC83→partner) and Y-score (partner→CCDC83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PRAMEF9 →	+0.013	+4.813	<.001	<.001	3	1
LARGE_INTESTINE	CCL18 →	+0.097	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	H1-7 →	+0.063	+3.807	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PRAMEF9 by CCDC83 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →