CCDC83

Across TCGA pan-cancer cohorts, CCDC83 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CCDC83 data layer compared with 3 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CCDC83 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCDC83 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LAML show a favorable association.

ACC, KIRC, and LGG are the cancer types where CCDC83 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.464	0.848	<.001	142	view →
KIRC	OS	Median	All	0.541	0.709	<.001	135	view →
LGG	DFS	Median	All	0.304	0.437	<.001	37	view →
HNSC	OS	Median	IV	0.315	0.603	.001	32	view →
DLBC	OS	Median	All	0.482	1.000	.011	31	view →
UCEC	DFS	Tertile	IV	0.870	0.501	.008	28	view →
LAML	DFS	Quartile	All	0.624	0.374	.019	24	view →
LIHC	OS	Tertile	All	0.668	0.810	.011	19	view →
SKCM	OS	Quartile	III,IV	0.291	0.448	.020	17	view →
LUSC	OS	Tertile	All	0.842	0.654	.011	16	view →
SCLC	DFS	Quartile	All	0.220	0.717	.001	14	view →
CHOL	DFS	Tertile	II,III,IV	0.699	0.131	.025	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CCDC83–ACC (DFS)

Open the ACC breakdown →