CCDC83

Across TCGA pan-cancer cohorts, CCDC83 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of CCDC83’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CCDC83 RNA is repressed in tumor relative to normal tissue. In most cancer types CCDC83 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, BRCA, and KIRC are the cancer types where CCDC83 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC83 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.039	<.001	9	view →
BRCA	Female	II,III,IV	+0.270	<.001	6	view →
KIRC	All	II,III,IV	−0.028	<.001	6	view →
PRAD	All	All	+0.346	<.001	2	view →
UCEC	All	IV	+0.125	.037	2	view →
LUSC	Male	III,IV	−0.025	.019	1	view →
KIRP	All	III,IV	−0.024	.044	1	view →
LIHC	All	All	+0.006	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

CCDC83–KICH

Open the KICH breakdown →