CCDC122

Across TCGA cell cohorts, CCDC122 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC122-associated genes across cancer lineages are C14orf180 and IL27. Each is linked with CCDC122 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC122-to-partner and partner-to-CCDC122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf180 grouped by CCDC122-low versus CCDC122-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC122→partner) and Y-score (partner→CCDC122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C14orf180 →	+0.126	+4.155	<.001	.003	3	1
LARGE_INTESTINE	IL27 →	+0.725	+3.823	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C14orf180 by CCDC122 expression — LARGE_INTESTINE

Explore this box plot interactively →