CBX6

Across TCGA patient cohorts, CBX6 mutation is significantly associated with the RNA expression of many other genes, with 2,101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBX6-associated genes across cancer lineages are RN7SL98P, UBR7, and OR1E3. Each is linked with CBX6 in more than 2 cancer types. Because this analysis shows association rather than direction, both CBX6-to-partner and partner-to-CBX6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL98P grouped by CBX6-low versus CBX6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX6→partner) and Y-score (partner→CBX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL98P →	+0.166	+3.956	.001	.002	3	3
UCEC	UBR7 →	+0.502	+2.375	<.001	<.001	3	3
LUSC	OR1E3 →	+0.062	+4.191	<.001	.009	3	2
LUSC	RNU6-1228P →	+0.218	+4.191	<.001	.009	3	2
LUSC	LINC01288 →	+0.129	+4.578	.001	.005	3	2
LUSC	MIR8066 →	+0.392	+3.932	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,101 associations by consensus.

RN7SL98P by CBX6 expression — COAD

Explore this box plot interactively →