CATSPER3

Across TCGA patient cohorts, CATSPER3 mutation is significantly associated with the RNA expression of many other genes, with 1,040 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CATSPER3-associated genes across cancer lineages are ASAH2B, HAUS3, and RDM1. Each is linked with CATSPER3 in more than 2 cancer types. Because this analysis shows association rather than direction, both CATSPER3-to-partner and partner-to-CATSPER3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASAH2B grouped by CATSPER3-low versus CATSPER3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CATSPER3→partner) and Y-score (partner→CATSPER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASAH2B →	+0.317	+1.971	.009	.009	3	3
UCEC	HAUS3 →	+0.430	+2.436	.005	.002	3	3
UCEC	RDM1 →	+0.664	+3.467	<.001	.002	3	2
BLCA	RNU6-104P →	+0.368	+6.051	<.001	<.001	3	2
UCEC	RNA5SP411 →	+1.312	+1.934	<.001	.005	3	2
SKCM	LINC01543 →	+0.200	+3.408	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,040 associations by consensus.

ASAH2B by CATSPER3 expression — UCEC

Explore this box plot interactively →